VI.2 制作的人类连接组

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Olaf Sporns

Patric Hagmann

左图是人脑解剖图,由Eugen Ludwig 和 Josef Klingler从尸体组织中构建的。解剖图展示了几大主要的人脑解剖特性,但它没有解释脑中联系。右图是展示了脑的解剖特性与大脑皮层的特定区域之间的联系。地图由生物医学工程师和神经学家Patric Hagmann于2008年从一个活体人类的磁共振成像数据中产生的。中图展示了计算认知神经学家Olaf Sporns使用科学网络工具制作的人类连接组。网络分析揭示了明显的小世界特性、枢纽区域互联的多模型和高度互联的脑区域组成的结构核心。随着多主体的多重数据得以分析,单独连接组展示了其特殊的结构特性,这可用来解释认知和行为的差异性。

Translation by:

Yunwei Chen, Chinese Academy of Sciences.


Hagmann, Patric, Leila Cammoun, Xavier Gigandet, Reto Meuli, Christopher J. Honey, Van J. Wedeen, and Olaf Sporns. 2008. “Mapping the Structural Core of Human Cerebral Cortex.” PLoS Biology 6 (7): 1479-1493.

Sporns, Olaf. 2011. Networks of the Brain. Cambridge, MA: MIT Press.

Sporns, Olaf, and Patric Hagmann. 2008. The Human Connectome. Courtesy of Little, Brown and Company, Patric Hagmann, and Olaf Sporns. In “6th Iteration (2009): Science Maps for Scholars,” Places & Spaces: Mapping Science, edited by Katy Börner and Elisha F. Hardy.

Acknowledgements: This exhibit is supported by the National Science Foundation under Grant No. IIS-0238261, CHE-0524661, IIS-0534909 and IIS-0715303, the James S. McDonnell Foundation; Thomson Reuters; the Cyberinfrastructure for Network Science Center, University Information Technology Services, and the School of Library and Information Science, all three at Indiana University. Some of the data used to generate the science maps is from the Web of Science by Thomson Reuters and Scopus by Elsevier. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.